I just tried a third computer running IE and had the same issue.
The device is the only one 4K IP camera on my network, no NVR. ( DS-2DE4A425IWG-E)
However, I think you might have identified the cause. The Good computer is a powerful Alienware, and the one Live View fails is a smaller Laptop with a 1.60Ghz processor and 32 GB RAM.