It certainly is possible to use IPv6, but there is a learning curve, so you will need to be willing and able to teach yourself. In the short term, it may be easier to use a third-party service like zerotier or ngrok to do remote access.
Here are some steps for IPv6 setup:
1. Assign a static IPv6 address to your
Blue Iris PC.
2. Add a firewall rule in your router to allow incoming traffic to the address (TCP protocol, only for the BI web server port number).
3. IPv6 addresses are long and unwieldy things. I strongly recommend getting a DNS AAAA record to point at your BI PC's static IPv6 address. Use that in the mobile app and/or web browser when you connect. Some
DDNS providers support IPv6 so I'm sure you can find a free option. I use no-ip but I have a paid plan and I'm not sure how good their free service is.
Remember you can only connect to IPv6 addresses from IPv6-enabled clients. Most cellular networks should have IPv6 enabled I think. But many homes and businesses will still not have it turned on so keep that in mind if you have trouble connecting remotely from some locations.