Reaction to Shingles vaccine

[lulu5kamz]

I got the earlier vaccine with the single shot and then later I got the 2 shot vaccine on advice of my doctor. I had no reaction to either of the vaccines. Before I retired, I worked in an office with a lady who got shingles. From her description, it does not seem like something I want to experience.

 

[David L]

Yeah my 78 year old uncle just went through it for 6 weeks. Very painful...

 

[David L]

I am just having a hard time verifying what is in the new shot. But I am not good at searching medical things out, I have a hard time understanding...

 

[samplenhold]

I am just having a hard time verifying what is in the new shot.

Not sure what you mean by "New Shot"? The Shingrix shot has been around for a while, before COVID. I doubt it is mRNA.

 

[fullboogie]

Just got over shingles at the age of 54. Aside from a kidney stone a few years ago, it is undoubtedly the most painful thing I've ever experienced. Had it on my head, jawline and neck. Absolutely fucking miserable. Even 10 weeks out, I can still feel tingling sensations in my scalp, and my jawline is still a little swollen. Holy hell, never again!

 

[mcapeed]

Just got over shingles at the age of 54. Aside from a kidney stone a few years ago, it is undoubtedly the most painful thing I've ever experienced. Had it on my head, jawline and neck. Absolutely fucking miserable. Even 10 weeks out, I can still feel tingling sensations in my scalp, and my jawline is still a little swollen. Holy hell, never again!

I have seen how miserable shingles can be. I’m wrestling with getting the vax. The pain and suffering can last for months. Just dont trust the medical establishment.


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[TonyR]

Just got over shingles at the age of 54. Aside from a kidney stone a few years ago, it is undoubtedly the most painful thing I've ever experienced. Had it on my head, jawline and neck. Absolutely fucking miserable. Even 10 weeks out, I can still feel tingling sensations in my scalp, and my jawline is still a little swollen. Holy hell, never again!

I hear ya. That's where I got them, Feb. 2017.
Over 5 years later, if I get super stressed or PO'd about something that same line tingles! Now that's weird.

I hope you get better soon, brother.

 

[sebastiantombs]

I haven't researched the shingles vaccine at all really, but I'll speculate it falls in to the "mab" family, monoclonal antibodies, rather than an mrna.

 

[jmhmcse]

SHINGRIX (Zoster Vaccine Recombinant, Adjuvanted), suspension for intramuscular injection

https://www.fda.gov/media/108597/download

extracted from the above document found on the FDA's website regarding Shingrix (RZV)

---------

SHINGRIX (Zoster Vaccine Recombinant, Adjuvanted) is a sterile suspension for intramuscular injection. The vaccine is supplied as a vial of lyophilized recombinant varicella zoster virus​

surface glycoprotein E (gE) antigen component, which must be reconstituted at the time of use with the accompanying vial of AS01B adjuvant suspension component. The lyophilized gE antigen component is presented in the form of a sterile white powder. The AS01B adjuvant suspension component is an opalescent, colorless to pale brownish liquid supplied in vials. The gE antigen is obtained by culturing genetically engineered Chinese Hamster Ovary cells, which carry a truncated gE gene, in media containing amino acids, with no albumin, antibiotics, or animal-derived proteins. The gE protein is purified by several chromatographic steps, formulated with excipients, filled into vials, and lyophilized.​

---------

would seem to be a vaccine created from the virus itself, similar to the annual flu shot.

<not a doctor. just a browser-user>

 

[David L]

When I did my searching I found a few articles like this about GSK using mRNA in their future vaccines. Just could not find if they have already altered the Shingrix yet.

GSK and CureVac announce strategic mRNA technology collaboration | GSK

Companies to collaborate on mRNA vaccine and monoclonal antibody research programmes in infectious diseases

www.gsk.com

 

[David L]

I think we are good, this is a later article, hopefully up to date:

Shingrix Shingles Vaccine

Shingrix zoster vaccine prevents shingles.

www.precisionvaccinations.com

 

[David L]

Thanks for everyone's help.

 

[David L]

I have seen how miserable shingles can be. I’m wrestling with getting the vax. The pain and suffering can last for months. Just dont trust the medical establishment.


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I am with you, if future vaccines are going to alter our DNA, count me out...

 

[David L]

Not sure what you mean by "New Shot"? The Shingrix shot has been around for a while, before COVID. I doubt it is mRNA.

Guess I got caught up in GSK article of their announcement for future vaccines to be mRNA-Based, just trying to see if their is a Newer Shingrix shot out...Thanks...We are feeling better about getting the shot now...or at least me...since the wife had a mild case she should be good if she gets it again, should be milder from what we are being told by everyone. I don't want to go through what fullboogie went through. I have had 5 kidney stones in my live so I know pain, but it is short lived compared to the weeks of nerve pain with Shingles. If I can prevent it with a shot, bring it on...

 

[Frankenscript]

@David L Here's the Shingrix official website describing it's mode of action:

Mechanism of Action | SHINGRIX (Zoster Vaccine Recombinant, Adjuvanted)

Learn more about the mechanism of action of SHINGRIX (Zoster Vaccine Recombinant, Adjuvanted), which uses an antigen/adjuvant system.

shingrixhcp.com

What's in the vaccine is a recombinant protein for part of the virus surface antigen, along with an adjuvant that makes it easier for the human immune system to react to the protein and form immunity against it.

What recombinant means, in this setting, is that the DNA sequence of the surface protein, actually just the sequence for one part of the protein, was used to produce a that specific protein sequence in quantity in a lab. The protein is purified, then mixed with the adjuvant and packaged. The vaccine contains no live virus, no killed virus, and creates a very specific immune response. The adjuvant is a chemical cocktail that keeps the protein folded properly during storage, injection, and in the body for a while, so that the protein maintains the right shape to look like the real virus-born protein, so that the immune response is an authentic one.

For the record, I've had both Shingrix shots. The first one gave me a goose egg at injection site, for several days it was painful (but not debilitating). The second shot gave me only mild pain at injection site for a day but gave me significant fatigue and body aches the day after, though I was fine the day after that. Everyone I know who has had Shingrix has reported similar effects. I know several people who got shingles as 55+ adults and it's not something I wish to experience. Mild, brief discomfort from the shot is to me well worth it to reduce the chance of getting shingles. It's not REALLY known how often a booster for Shingrix will be needed, because it's too new. It is known that Shingrix is much more effective than Zostavax and it lasts much longer. Zostavax, though worthwhile in its time, did have a fair amount of side effects, such that moving to Shingrix as the primary vaccine, makes sense.

I hope this is helpful. There's a good video at the Shingrix site.

 

[Timokreon]

I had the shots a couple years ago. First shot, pharmacist stated to me about all the side effects, etc.. I ended up with a sore arm around the injection site for a day. 2nd shot, same pharmacist telling me how it's going to be the worst shot I've ever gotten, I smile, nod..
2nd shot, mild soreness around the injection site for a few hours.

I've had shots back decades ago that knocked me on my butt from that wonderful black injection gun. This particular set of shots, for me, was nothing.

 

[fullboogie]

I hear ya. That's where I got them, Feb. 2017.
Over 5 years later, if I get super stressed or PO'd about something that same line tingles! Now that's weird.

I hope you get better soon, brother.

Wow, 5 years later. It almost feels like the pins-and-needles you get in your leg when it's asleep.

 

[TonyR]

Wow, 5 years later. It almost feels like the pins-and-needles you get in your leg when it's asleep.

Yep, exactly.

 

[Coldair]

the covid rashes are far worse, I have been battling since last July my back looks like I got a severe sunburn than got shot with dove shot my right leg as what looks like permanent poision ivy

 

[mcapeed]

the covid rashes are far worse, I have been battling since last July my back looks like I got a severe sunburn than got shot with dove shot my right leg as what looks like permanent poision ivy

What caused the rash?


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