Is it not storing the new settings or rather the camera's (normal) behavior of always switching from profile being adjusted back to the profile that was set as the active profile.
Remember, selecting a profile and making adjustments to its settings does so with the profile being edited temporarily activated during adjustments. Once you leave the web GUI adjustments page, the active profile takes back over.
The active profile is the one that is current scheduled.
BTW: If you use day/night utility with the new Web GUI, you also must perform the work around dance of selecting "self-adaptive" profile in the GUI before leaving the page. Doing so, enables the API calls that day/night uses to set profile. Otherwise, the commands from day/night utility are ignored. The camera will be in the wrong mode, but be responsive to day/night commands. Finally let day/night to activate the desired day or night profile.