factor01, thanks for being helpful, but no, none of this has any effect.
I already excluded all my drives (ie entire C:, D:, and network share) as I have been troubleshooting this for 6+ months.
Tamper Protection is also already off.
When real-time protection is off, my CPU runs at no higher than 5-6%. As soon as it's on, it's anywhere between 14-30%, and my FPS drops to 1-5 PFS. Everything in BI is sluggish. Even logging into the computer is slow.
As SOON as I kill real-time protection, or BI, the computer snaps back to normal.