I've gone back and read the thread though in detail, previously I just skimmed a few posts - I rarely have time to read in detail. It doesn't sound like any issue with your pc or specs, especially as you've monitored your system resources which are fine, and your pc is so cutting edge.
There's an updated version of BI available 4.6.4.8, might be worth a try as there's a possibility there could have been a bug in 4.6.4.6.
Also, if nothing else, it might solve an issue with the current drivers or software installation as Fenderman suggested.
Personally, I'd do a clean installation. If there are drivers, delete them as well as the program. You could contact support to see if there's a clean uninstallation tool available. Failing that, just delete everything you can that's related to the current version, drivers, software, folders etc, then start afresh with 4.6.4.8 and see how it pans out. If you have a licence file, just remember to ensure you have a copy before deleting the containing folder.