There were the usual google docs etc, which I have disabled, but nothing else.
I have also noticed that it is live in 'window' mode but it is 'full screen' where there is a problem.
Full screen mode still works fine for me in Chrome. Try updating your graphics driver on the PC having this problem. If I recall, Edge and Firefox both use the JavaScript H.264 player by default, which does not support hardware acceleration, and therefore would be less susceptible to driver bugs.
Only extension in Chrome is LastPass. With IE & Edge I point them at the same address as Chrome and they work.
The LastPass extension doesn't cause any issues for me. It is possible you can learn more about what is going wrong by opening Chrome's developer tools and looking on the Console and Network tabs when UI3 tries to load. There may be additional clues such as the browser warning about certain problems in the console.