Anything is possible, but most here, especially with a camera zoomed all the way in, has shown that the area of focus is a lot smaller and not focused for the entire frame and will result in blurry elsewhere. Now whether it is enough to worry about is another story.
I suggest you have someone go out and stop at say three locations (left, right, and middle) and then focus and I suspect you will see the focus number will be different for each one. Make sure you set the step count for the focus to 1 because if it is on the default 20, then it won't show you the focus number changing a few numbers unless it is more than a 10 step difference.
We have several threads scattered throughout that shows this. Folks have even put reflective tape on either side of the road to demonstrate how depending on where you set the focus, the areas outside of that could be out of focus. It is why for LPR we say to have someone stop a car in the ideal area you want to get a capture and get the focus number in the 1step range to get a good number.
You then need to decide which one is the one you want to get the clean focus or average the focus numbers of the 3 spots and then recognize it won't be clean and crisp everywhere, but may be readable from more distances.
Even with my tight image where a car is in and out of the frame in under 0.5 seconds, as it gets close to and outside the red box, it gets blurry. The focus numbers starting top right corner to center to bottom left corner were different by 10 steps. So I can either go with the clear focus step in the center and can still read the plates outside of that, but they will be a little blurry or do an average of the focus number and maybe be a little blurry across the image but still readable.